Spravato for Depression

How Spravato Helps With Depression Treatment
Spravato acts differently from traditional antidepressants. Here’s how it can change the treatment landscape for patients:
- Rapid Acting: Spravato can alleviate depressive symptoms much faster than many other antidepressants, with some patients feeling better within hours of the first dose.
- Targeted Therapy: It targets the NMDA receptor in the brain, a different approach than most antidepressants, which typically affect serotonin or norepinephrine.
- Administration and Monitoring: Treatment involves administration under medical supervision in a healthcare setting to monitor its effects and ensure patient safety.
What is Spravato?
Treatment Process with Spravato at Brandon TMS and Psychiatry
Here’s what patients can expect when undergoing treatment with Spravato:
- Initial Consultation: Professional evaluation to determine if Spravato is the right treatment option.
- Supervised Administration: Spravato is administered twice a week for an initial period in our office, under the supervision of healthcare professionals.
- Ongoing Assessment: Continuous monitoring of symptoms and side effects to adjust the treatment plan as necessary.
Benefits of Using Spravato for Depression
Patients choosing Spravato may experience several benefits:
- Quick Symptom Improvement: Many report rapid relief from depressive symptoms, which can be life-changing for those who have struggled with long-term depression.
- New Treatment Avenue: Offers a new option for patients who have tried and not responded to multiple other antidepressants.
- Comprehensive Care: At Brandon TMS and Psychiatry, Spravato is part of a broader, individualized care plan that includes other therapies and support.
Spravato presents a promising new avenue for depression treatment, particularly for those who have not found relief with traditional therapies. Our practice is committed to providing this innovative treatment, helping to restore hope and improve the quality of life for our patients.

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HAVE QUESTIONS?
FAQ - Spravato for Depression
Spravato is a nasal spray formulation of esketamine, a derivative of ketamine, approved by the FDA for the treatment of treatment-resistant depression (TRD) in adults. It is used in conjunction with an oral antidepressant in a supervised healthcare setting.
Spravato works by modulating glutamate neurotransmission in the brain, specifically targeting the N-methyl-D-aspartate (NMDA) receptor. By rapidly increasing levels of glutamate, Spravato helps to restore synaptic connections and neural plasticity, which are believed to play a role in depression.
Spravato is indicated for adults with treatment-resistant depression (TRD), defined as depression that has not responded adequately to at least two different antidepressant treatments of adequate dose and duration in the current depressive episode.
Spravato is administered as a nasal spray under the supervision of a healthcare provider in a certified healthcare facility. The treatment involves self-administration of the nasal spray device under the observation of a healthcare professional.
Spravato has shown rapid and robust antidepressant effects in some individuals with treatment-resistant depression. However, there are potential risks and side effects associated with Spravato, including dissociation, sedation, dizziness, increased blood pressure, and potential for abuse or misuse. It's essential to undergo Spravato treatment under the supervision of a qualified healthcare provider in a clinical setting.